ScaleReady Celebrates Seattle Children's Win with G-Rex Grant

ScaleReady's G-Rex Grant Awarded to Seattle Children's Therapeutics

ScaleReady, in partnership with Wilson Wolf Manufacturing and Bio-Techne Corporation, has exciting news to share. Seattle Children's Therapeutics has recently been honored with a substantial G-Rex Grant, which amounts to $125,000. This funding aims to bolster the development of their CAR-T cell platform, integrating cutting-edge advancements that will significantly enhance their capabilities.

Significance of the G-Rex Grant

According to Christopher Brown, the Director of GMP Manufacturing at Seattle Children's Therapeutics, this technology is central to their CAR-T platform, having successfully provided cell therapy to numerous clinical trial participants using G-Rex bioreactors. This grant not only symbolizes recognition but also represents a strategic step forward in improving patient treatment options.

Expert Insights and Future Challenges

John Wilson, CEO of Wilson Wolf and co-inventor of G-Rex, shared his enthusiasm for this initiative, stating how Seattle Children's is uniquely positioned within the scientific community. The organization consists of exemplary scientists, physicians, and engineers dedicated to helping cancer patients. The G-Rex Grant Program is described as a fantastic opportunity for them to simplify the therapy production process further.

Innovations Under the G-Rex Grant

As part of this award, Seattle Children's Therapeutics will explore a diverse range of fully closed G-Rex bioreactors and access GMP-grade cytokines from Bio-Techne. This initiative aims to refine their manufacturing processes not only for CAR-T trials but other future clinical avenues. Through this program, Seattle Children's will also gain early insight into G-Rex's pipeline, enabling them to partake in the evaluation of new device innovations, including advanced T-cell isolation technology.

ScaleReady's Commitment to Cell Therapy

ScaleReady's commitment to pushing the boundaries of cell and gene-modified therapies is evident through their G-Rex Grant Program. Valued at $20 million, this initiative is designed to propel advancements in cell therapy development by offering individual grants of up to $300,000. Recipients of these awards will benefit from exclusive resources available through ScaleReady’s expanding network of G-Rex Grant Partners, who possess top-tier expertise in various critical areas.

Transforming the CGT Landscape

The G-Rex manufacturing platform has gained traction among over 800 organizations, now responsible for producing drug products pivotal to about 50% of ongoing CGT clinical trials. This expansive reach not only illustrates the platform's efficacy but also highlights how CGT companies can significantly reduce time and costs on their journey to commercialization.

About the Organizations Involved

About ScaleReady
ScaleReady provides the cell and gene-modified cell therapy sector with an innovative manufacturing platform centered on G-Rex technology, enabling practical and scalable drug development.

About Wilson Wolf Manufacturing
Wilson Wolf focuses on streamlining CGT research and manufacturing processes through its G-Rex technology, actively utilized in diverse applications globally. Their mission underscores a commitment to generating hope for those battling cancer.

About Bio-Techne Corporation
Bio-Techne Corporation (NASDAQ: TECH) is a pivotal entity in life sciences, supplying innovative tools and bioactive reagents tailored for research and clinical diagnostics. Their collaboration with Wilson Wolf has led to the development of products specifically designed for G-Rex bioreactors, increasing accessibility and efficiency in the manufacturing process.

Frequently Asked Questions

What is the G-Rex Grant?

The G-Rex Grant is a funding program designed to support advances in cell and gene-modified cell therapy, enabling research institutions to enhance their manufacturing capabilities.

How much funding did Seattle Children's receive?

Seattle Children's Therapeutics was awarded $125,000 through the G-Rex Grant to further develop their CAR-T cell platform.

What role does ScaleReady play in the CGT field?

ScaleReady supports cell and gene therapy development by providing innovative manufacturing solutions and grants that facilitate research and clinical trials.

How can the G-Rex Grant impact cancer treatment?

This grant will allow Seattle Children's to innovate their CAR-T therapy manufacturing, potentially leading to improved treatment options for cancer patients.

What is Bio-Techne's involvement in this initiative?

Bio-Techne collaborates with Wilson Wolf in developing essential tools and reagents tailored specifically for use in G-Rex bioreactors to improve high-throughput manufacturing processes.

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