RNAConnect Launches Groundbreaking cDNA Synthesis Kit for Researchers
Introducing the UltraMarathonRT cDNA Kit
RNAConnect, recognized as a frontrunner in next-generation molecular biology tools, is proud to announce the commercial launch of its UltraMarathonRT cDNA Synthesis and Amplification Kit. This innovative product is designed to transform short-read RNA sequencing workflows, significantly improving both sensitivity and the breadth of transcript detection.
Pioneering Technology for RNA Sequencing
The UltraMarathonRT (uMRT) technology encapsulates a major advancement in the field of RNA sequencing. Dr. Jason Underwood, Vice President of Technology Development at RNAConnect, emphasizes this impact: "UltraMarathonRT represents a significant leap forward for RNA-seq. Researchers can now uncover RNA species and transcriptional complexity that were previously masked, enabling new avenues for biomarker discovery and fundamental research." This capability is especially beneficial for discovering rare isoforms and long noncoding RNAs, which are critical in various biological processes.
Overcoming Limitations in Current Technologies
Despite advancements in RNA sequencing technologies, one persistent issue has been the challenge of accurately replicating the diversity of transcripts in RNA samples. Traditional retroviral reverse transcriptases (RTs) have limitations; they are often distributive and struggle with long or highly structured RNA sequences, leading to incomplete cDNA generation. This can result in significant gaps in cDNA libraries, impeding successful sequencing.
Advantages of the UltraMarathonRT Kit
The UltraMarathonRT Synthesis and Amplification Kit addresses these challenges through its unique group II intron encoded reverse transcriptase. This RT boasts an intrinsic helicase activity, which allows it to synthesize cDNA efficiently and accurately, covering RNA sequences end-to-end in a single pass at ambient temperatures.
Key Features and Performance
Key benefits of the UltraMarathonRT cDNA Synthesis and Amplification Kit include:
- Enhanced detection of genes, isoforms, and retained introns: The uMRT significantly boosts reverse transcription for low-abundance and complex RNAs, capturing important transcripts that are often missed with conventional RT kits.
- Superior quantification for long transcripts: Its ultra-processive and high-fidelity reverse transcriptase ensures accurate full-length cDNA synthesis, facilitating precise quantification of long genes.
- Broad compatibility with existing RNA-seq workflows: The UltraMarathonRT kit seamlessly integrates into standard Illumina® platforms and library preparation protocols, making it ideal for various research applications such as differential expression studies, biomarker research, and more.
Availability and Custom Solutions
The UltraMarathonRT cDNA Synthesis and Amplification Kit is now commercially available across major global markets, offering flexible kit sizes suitable for everything from pilot studies to high-throughput workflows. Additionally, custom OEM and bulk packaging options are on offer, catering to large-scale users and core facilities.
About RNAConnect
RNAConnect is a dedicated life science tools company focused on pioneering RNA analysis solutions that enhance research in genomics, transcriptomics, and molecular diagnostics. Committed to providing scientists with reliable and accurate tools, RNAConnect helps facilitate groundbreaking discoveries across various fields including rare diseases, oncology, immunology, and neurobiology.
Frequently Asked Questions
What is the UltraMarathonRT cDNA Kit?
The UltraMarathonRT cDNA Kit is a new product from RNAConnect that significantly improves RNA sequencing workflow by enhancing transcript detection capabilities.
How does the UltraMarathonRT improve RNA sequencing?
This kit allows researchers to identify complex RNA species and transcriptional variations, particularly for rare isoforms and long noncoding RNAs, that other kits may miss.
What are the main advantages of using this kit?
Main advantages include enhanced detection of difficult-to-replicate RNA sequences, precise quantification of long transcripts, and broad compatibility with existing sequencing protocols.
Where can I purchase the UltraMarathonRT cDNA Kit?
The kit is available for purchase worldwide through RNAConnect, with options for various research scale needs.
What is the commitment of RNAConnect?
RNAConnect is committed to innovating RNA analysis solutions that empower scientists and advance research in various fields of life sciences.
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