Revolutionizing Biologics Delivery: Surf Bio's New Approach
Revolutionizing Biologics Delivery
In a significant advancement for the biopharmaceutical industry, Surf Bio has announced a peer-reviewed publication highlighting the feasibility of delivering high-concentration biologics subcutaneously. Researchers conducted this study in conjunction with Stanford University, and the findings, published in a prominent medical journal, bring new hope for patients reliant on complex drug therapies.
Breakthrough Research on Drug Delivery
The study, led by Dr. Carolyn Jons and her team, explored the potential of reformulating biologics into ultra-high concentrations exceeding 500 mg/mL. This remarkable achievement suggests that patients could be given doses traditionally saved for intravenous infusions now using standard subcutaneous injections. This shift could ease the burden on healthcare systems by allowing self-administration at home.
Innovative Microparticle Formulation
One of the breakthroughs highlighted in the research is the use of a spray-drying technique that transforms liquid protein formulations into microparticles. These tiny particles can be suspended in a non-solvent liquid, resulting in a stable solution suitable for injection. By utilizing a standard 27-gauge needle for administration, the methodology opens doors for easier patient access to biologic therapeutics.
Advancing Patient-Friendly Solutions
Surf Bio’s commitment to developing patient-friendly drug delivery systems is evident in their SnapShot™ technology platform. CEO Bryan Mazlish remarked on the platform's potential, stating, "Our work at Surf Bio aims to ensure that therapies needing infusion can be simplified for everyday use, enhancing patient experience and independence." This innovation positions Surf Bio as a leader in tackling the challenges of biologic therapy delivery.
Clinical Implications of the Study
The implications of this study are vast. Many traditional biologics require patients to visit clinics or hospitals for administration, which can be a significant barrier to treatment. The ability to self-administer medications at home could lead to better compliance and health outcomes, particularly for those with chronic conditions where regular treatment is critical.
Technological Advances and Stability
This innovative platform employs a polymer excipient that provides stability during the spray-drying process and improves the injectability of the final formulation. Research has shown that these microparticles not only maintain the integrity of the proteins but also demonstrate sustained release and efficacy beyond currently available subcutaneous options.
About Surf Bio
Surf Bio is set to disrupt the biopharmaceutical landscape with its transformative SnapShot™ technology. This platform allows the development of ultra-concentrated monoclonal antibodies and biologics, facilitating their use in a single, user-friendly injection. The company's technology emerged from research at Stanford University and was founded by experts from Bigfoot Biomedical and AGC. They aim to change the way biologics are administered, making them more accessible to patients in need.
Contact Information
To learn more about Surf Bio and its groundbreaking work, interested parties can reach out to Tiberend Strategic Advisors, Inc., which serves as a contact point for the company.
Frequently Asked Questions
What is the key finding of Surf Bio's recent publication?
The study demonstrates the feasibility of delivering ultra-concentrated biologics via subcutaneous injection, potentially revolutionizing patient access to treatments.
Who conducted the research featured in the publication?
The research was conducted by a team from Stanford University, led by Dr. Carolyn Jons.
What is SnapShot™ technology?
SnapShot™ is Surf Bio's proprietary platform that enables the formulation of high-concentration biologics for easier administration.
How does this research impact patient care?
It simplifies the administration of biologics by allowing self-injection at home, reducing the necessity for hospital visits.
What does this mean for the future of biologics?
This approach could significantly enhance the landscape of drug delivery, making potent therapies more accessible and less burdensome for patients.
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