ReCode Therapeutics Secures Major Funding for mRNA Therapies
ReCode Therapeutics Secures Additional Financing
ReCode Therapeutics, a pioneering clinical-stage genetic medicines company focused on precision delivery, has recently finalized over $29 million in additional funding. This substantial investment aims to further its research and development of cutting-edge mRNA and gene editing therapies. The support is bolstered by collaboration with the Cystic Fibrosis Foundation and a new partnership with Praxis Precision Medicines, Inc. (NASDAQ: PRAX), highlighting ReCode's commitment to advancing innovative treatment options for those with difficult-to-treat genetic conditions.
Support from the Cystic Fibrosis Foundation
The Cystic Fibrosis Foundation has notably increased its support by contributing an additional $3 million. This funding will specifically target the advanced stages of the Phase 2 clinical trial for RCT2100, an inhaled mRNA therapy aimed at providing functional CFTR protein to lung cells of individuals with cystic fibrosis (CF). This additional financing emphasizes the Foundation's robust commitment to ReCode's research initiatives, bringing its total investment to $33 million.
Importance of RCT2100
RCT2100 has been designed to be a significant breakthrough for the 10% of cystic fibrosis patients who experience mutations in the CFTR gene that do not respond to existing treatments. By delivering a correct version of the CFTR mRNA directly to lung cells, RCT2100 offers hope for many who currently have limited options, including those with rare mutations.
Collaboration with Praxis Precision Medicines
ReCode has formed a strategic partnership with Praxis Precision Medicines, focused on developing lipid nanoparticle (LNP) formulations to improve the delivery of antisense oligonucleotides (ASOs) to areas of the brain that are often overlooked. This collaboration exemplifies the integration of genetic insights into actionable therapeutic strategies, potentially enhancing treatment efficacy for central nervous system disorders.
Impact of the Partnership
This partnership aims to create a well-tolerated LNP formulation that can optimize ASO delivery, which is crucial for treating a variety of neurological conditions. Targeting underexposed brain regions can significantly improve patient outcomes and broaden the therapeutic options available for complex genetic disorders.
Participation in Key Conferences
ReCode's leadership team is committed to sharing their advancements and innovations at prominent scientific gatherings. They will attend the upcoming European Respiratory Society (ERS) Congress in Amsterdam and the North American Cystic Fibrosis Conference (NACFC) in Seattle. These events provide excellent opportunities for networking, sharing knowledge, and showcasing the company's progress in genetic medicines.
Networking Opportunities
Participating in such conferences allows ReCode to engage with other leaders in the field, further enhancing its collaborative efforts and opening doors for future partnerships. These interactions are integral to staying at the forefront of mRNA and gene therapy innovations.
About ReCode Therapeutics
ReCode Therapeutics is dedicated to advancing the next generation of genetic medicines through its proprietary Selective Organ Targeting (SORT) lipid nanoparticle platform. This technology facilitates highly targeted delivery of genetic therapies right to the affected organs, cells, and tissues. By harnessing this precision delivery system, ReCode is at the forefront of offering transformative treatment options to patients with genetic disorders.
Lead Therapeutic Programs
The company’s lead assets, RCT2100 and RCT1100, focus on treating cystic fibrosis and primary ciliary dyskinesia, respectively. Both are formulated with the SORT LNP technology, marking a significant advancement in inhaled therapies designed to address the underlying causes of these conditions.
Frequently Asked Questions
What recent funding has ReCode Therapeutics secured?
ReCode Therapeutics secured over $29 million to advance its genetic medicines pipeline and enhance its ongoing clinical trials.
How is the Cystic Fibrosis Foundation involved?
The Cystic Fibrosis Foundation is supporting ReCode with an additional $3 million to further the development of RCT2100, a critical mRNA therapy.
What is RCT2100 designed to do?
RCT2100 is aimed at treating patients with cystic fibrosis by delivering a correct copy of the CFTR mRNA directly to lung cells to help produce functional CFTR protein.
What partnerships has ReCode established recently?
ReCode has partnered with Praxis Precision Medicines to improve the delivery systems for genetic therapies using lipid nanoparticle formulations.
Where will ReCode be presenting its research?
ReCode's leadership will participate in the European Respiratory Society Congress and the North American Cystic Fibrosis Conference to present their innovations and network with industry experts.
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