Psilera Teams with Hesperos to Enhance FTD Drug Development
Psilera and Hesperos Join Forces for Neurodegenerative Research
In an exciting development for the biotech field, Psilera, Inc., a cutting-edge biotechnology company focused on creating innovative therapies for complex neurological disorders, has forged a partnership with Hesperos Inc., a recognized leader in organ-on-a-chip technology. This strategic arrangement aims to propel the preclinical development of Psilera's promising drug candidate, PSIL-006, specifically targeting the challenges posed by frontotemporal dementia (FTD).
Harnessing Advanced Technology in Drug Development
The collaboration will utilize Hesperos’ proprietary Human-on-a-Chip platform, which seamlessly integrates patient-derived induced pluripotent stem cells (iPSCs) into sophisticated multi-organ systems. This state-of-the-art modeling technique enables the precise assessment of drug efficacy and safety, a method that has recently gained attention from regulatory bodies for its potential to minimize reliance on animal testing.
Quote from Psilera's Chief Scientific Officer
Dr. Jackie von Salm, Co-Founder and Chief Scientific Officer at Psilera, expressed enthusiasm about the partnership: "Our collaboration with Hesperos signifies a tremendous advancement in our objective to formulate new therapies for neurodegenerative diseases. Leveraging their innovative platform provides us with deeper insights into how PSIL-006 operates, guiding us in designing forthcoming first-in-human trials."
Significance of Hesperos' Technology
Hesperos' cutting-edge platform has gained accolades for its capability to mimic human physiological reactions, producing invaluable information regarding drug interactions across various organ systems. This technology has successfully supported numerous Investigational New Drug (IND) and Orphan Drug Designation (ODD) submissions, showcasing its effectiveness in ushering drug candidates toward clinical trials.
Potential Impact of PSIL-006 on Frontotemporal Dementia
FTD represents a debilitating condition characterized by progressive neurodegeneration, with scarce treatment options currently available. The incorporation of the advanced neuroplastogen PSIL-006 with Hesperos’ sophisticated biological modeling system aims to create targeted therapies that fill this critical medical gap. Results stemming from the preclinical modeling conducted by Psilera are anticipated to surface soon, providing vital data.
Expert Insights from Hesperos
Dr. James Hickman, Co-Founder and Chief Scientist of Hesperos, shared his excitement about the collaboration: "Partnering with Psilera as they advance next-generation neuroplastogens presents a unique opportunity. Our platform allows for the assessment of the compound's effects on neural tissues derived from patients with neurodegeneration, potentially fast-tracking the development of much-needed therapies utilizing clinically relevant insights."
About Psilera
Psilera is dedicated to developing breakthrough therapeutics that address complex neurodegenerative conditions. Through its innovative neuroplastogen drug design platform, the company has developed an impressive pipeline of next-generation assets, including PSIL-006. This first-in-class therapeutic aims to improve the lives of individuals coping with frontotemporal dementia (FTD) through scientifically rigorous and patient-centered approaches. Psilera is committed to reshaping the future of mindful medicine.
About Hesperos
Hesperos is a global contract research organization (CRO) specializing in preclinical drug development services, employing its Human-on-a-Chip platform. This approach helps in effectively replicating crucial aspects of human biology, significantly reducing the need for costly and time-consuming animal testing. Hesperos provides product development teams with more accurate insights that can predict therapeutic outcomes, thereby enhancing efficiency in drug development.
Frequently Asked Questions
What is PSIL-006?
PSIL-006 is a groundbreaking neuroplastogen drug candidate being developed by Psilera, specifically targeting frontotemporal dementia (FTD).
How does the partnership with Hesperos benefit Psilera?
The collaboration enables Psilera to leverage Hesperos' advanced Human-on-a-Chip technology for more accurate preclinical modeling and evaluation of PSIL-006.
What is frontotemporal dementia?
Frontotemporal dementia (FTD) is a progressive brain disorder characterized by changes in personality, behavior, and language skills, leading to significant cognitive decline.
What are the advantages of the Human-on-a-Chip platform?
The platform allows for the simulation of human organ systems, providing critical insights into drug efficacy and safety, while reducing reliance on animal models.
When can we expect results from the preclinical studies?
Results from Psilera's preclinical modeling efforts are anticipated to be available soon, specifically in the coming years.
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