Poxel Achieves Major Sales Milestone with TWYMEEG in Japan

Poxel Achieves Major Sales Milestone with TWYMEEG in Japan

In an exciting development, Poxel SA has announced a significant achievement with its product, TWYMEEG^®. This innovative treatment designed for managing type 2 diabetes has recorded net sales reaching JPY 5 billion in Japan, approximately EUR 30.6 million. This threshold marks a pivotal moment for Poxel, as it qualifies for positive net royalties and a sales-based payment, illustrating the successful market acceptance of TWYMEEG^®.

Understanding the Financial Implications

With net sales hitting this impressive figure, Poxel is set to receive a 10% royalty on all sales of TWYMEEG^® during Sumitomo Pharma’s fiscal year 2024. Furthermore, Poxel will benefit from a sales-based payment amounting to JPY 500 million. These financial gains highlight the product’s robust performance in the competitive pharmaceutical landscape of Japan.

CEO Insights on Revenue Growth

Thomas Kuhn, the Chief Executive Officer of Poxel, expressed optimism about these developments. He remarked, “We are particularly proud that our product has reached this contractual sales threshold in Japan, providing us with escalating net royalties despite our obligations to Merck Serono.” His statements reflect the confidence Poxel has in their product's longevity in the market and the expansion of revenue opportunities.

Future Financial Outlook for Poxel

Following this success, Poxel anticipates a continuous upward trajectory in royalties and payments as TWYMEEG^® further establishes its market presence. The ongoing discussions between Sumitomo Pharma and Japanese authorities to possibly update TWYMEEG^®'s package insert specifically for diabetic patients with renal impairment stands to bolster sales even further, potentially leading to greater royalty earnings in months to come.

Poxel's Strategic Partnerships and Innovations

Poxel operates in the dynamic field of biopharmaceuticals, concentrating on the development of innovative treatments for chronic and serious metabolic diseases. The company has positioned itself as a leader in treating conditions such as metabolic dysfunction-associated steatohepatitis (MASH) and rare metabolic disorders. The relationship with Sumitomo Pharma plays a crucial role in expanding Poxel's reach and financial stability.

Poxel’s Product Portfolio

In addition to TWYMEEG^®, Poxel is making strides with other products, such as PXL065 and PXL770. PXL065 targets metabolic diseases, having met its primary endpoint in the DESTINY-1 study, while PXL770 focuses on rare disorders. These innovative treatments, backed by clinical trials, highlight Poxel's commitment to advancing healthcare options for patients worldwide.

Poxel’s Financial Strategies Moving Forward

Poxel is strategically managing its finances, especially considering the impending repayment obligations stemming from agreements with partners. As of March 31, 2025, the company projects that its debt levels will hover around EUR 9.3 million, including payments from its reserve deposit accounts.

As Poxel continues to build on its success with TWYMEEG^® in Japan, its future appears promising. The potential for increased royalties indicates a healthy growth trajectory that could benefit both the company and its stakeholders.

Frequently Asked Questions

What is TWYMEEG^®?

TWYMEEG^® is a first-in-class product developed by Poxel for the treatment of type 2 diabetes, which is part of its strategic partnership with Sumitomo Pharma.

How much did TWYMEEG^® make in sales?

In Japan, TWYMEEG^® achieved net sales of JPY 5 billion, approximately EUR 30.6 million, which qualifies Poxel for royalty payments.

What royalties will Poxel receive?

Poxel is entitled to receive a 10% royalty on all sales of TWYMEEG^® during Sumitomo Pharma’s fiscal year 2024.

What other products is Poxel developing?

Poxel is also developing PXL065 for chronic diseases and PXL770 for rare metabolic disorders, expanding its innovative treatment portfolio.

What impact does this achievement have on Poxel’s financial future?

This milestone significantly enhances Poxel’s revenue potential and offers a strong outlook for future financial health through increased royalties and sales payments.

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