Posted On: 09/27/2013 11:52:23 PM
Post# of 72436
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Seel, in the Brilacidin 2B trial how many (is it arms?) would you say they will test to see which is the best dosage and frequency for treating patients? What would be expected patients per arm in a phase 2B? Would you expect the 2B to last less than 2,4,6 months?
I realize Kevetrin still has a long ways to go but to date it sure has been all one could expect IMO.
Being it is a drug for terminal patients, I would sure like to see the trial now split into a slow increase in dosage arm and an aggressive increase in dosage arm. Should something go wrong, you have sacrificed a few for the sake of the many. I know they could find a few patients willing to go the aggressive route with the PKK and other data they have accumulated to date showing low safety hazard. I understand in medicine today this is totally out of the question, but with the positive results so far for Kevetrin and the lack of terrible side effects, could you ever envision some plan such as I postured even being considered?
I realize Kevetrin still has a long ways to go but to date it sure has been all one could expect IMO.
Being it is a drug for terminal patients, I would sure like to see the trial now split into a slow increase in dosage arm and an aggressive increase in dosage arm. Should something go wrong, you have sacrificed a few for the sake of the many. I know they could find a few patients willing to go the aggressive route with the PKK and other data they have accumulated to date showing low safety hazard. I understand in medicine today this is totally out of the question, but with the positive results so far for Kevetrin and the lack of terrible side effects, could you ever envision some plan such as I postured even being considered?
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