Dr. Jamie Koufman, internationally renowned expert on reflux, and researcher Dr. Nikki Johnston studied how alkaline water destroyed pepsin, a stomach enzyme that when activated by acid causes painful reflux symptoms that can lead to cancer. According to the findings, natural artesian alkaline water instantaneously inactivated human pepsin in laboratory studies. Ordinary tap and bottled waters had no such effect. (Annals of Otology, Rhinology & Laryngology, July, 2012) $WTER