This is a good point. If enough docs agree to use leronlimab for EIND and maybe Right to Try. Maybe FDA will let these patients start at 700 mg and let them check PDL-1 within 3 months if doc and patient request it since it is outside of trial protocol.

If the data is good, this may be a back door to get the trial amended sooner if the direct approach does not work with FDA. In a way, this might have been strategized by Dr. J and be opportunistic as well as altruistic on his part.