(Total Views: 486)
Posted On: 08/31/2025 3:13:56 PM
Post# of 156696

[00:20:08] The women who were enrolled in these studies were very advanced patients who had fourth-line therapy; they had failed two lines in the metastatic setting."
Dr. J said his 1st contact was with Univ. of Arizona.
Look @ this Feb. 2022 Abstract & Sima Ehsani. Most likely was who Dr. J spoke with
But, from Abstract of the trial:
".....patients with CCR5+ mTNBC who are naïve to chemotherapy in the metastatic setting or who have failed first-line combination of chemotherapy (excluding carboplatin) and a checkpoint inhibitor in the metastatic setting."
https://www.researchgate.net/publication/3591...ncer_mTNBC
___
I thought we had only accepted ICI's failing in the higher lines of treatment --- this is just stunning.
& adds to the significant affect of LL to all ICI's.
I mentioned couple weeks ago expecting we'll announce a trial for the early mTNBC lines too....
Now with actually reading we accepted 1st line ICI failures...we have data to justify testing all lines
Once FDA acceptss the Briefing Book as valid & all additional programs & protocols.....it's YES!!..time.
With the flood gates on news, going wide-open...
Dr. J said his 1st contact was with Univ. of Arizona.
Look @ this Feb. 2022 Abstract & Sima Ehsani. Most likely was who Dr. J spoke with
But, from Abstract of the trial:
".....patients with CCR5+ mTNBC who are naïve to chemotherapy in the metastatic setting or who have failed first-line combination of chemotherapy (excluding carboplatin) and a checkpoint inhibitor in the metastatic setting."
https://www.researchgate.net/publication/3591...ncer_mTNBC
___
I thought we had only accepted ICI's failing in the higher lines of treatment --- this is just stunning.
& adds to the significant affect of LL to all ICI's.
I mentioned couple weeks ago expecting we'll announce a trial for the early mTNBC lines too....
Now with actually reading we accepted 1st line ICI failures...we have data to justify testing all lines
Once FDA acceptss the Briefing Book as valid & all additional programs & protocols.....it's YES!!..time.
With the flood gates on news, going wide-open...

