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Posted On: 08/09/2025 2:50:16 AM
Post# of 155736
My writes:
That doesn't seem right, since it works so much faster than that. Here's one citation that notes 100% CCR5 RO within hours...
This is from a 2021 article by Sacha, Hansen, Recknor et al.
https://www.frontiersin.org/journals/immunolo...;id=794638
Quote:
I have read in our patent applications & patents, 13 to 38 weeks for Leronlimab to fully occupy CCR5 receptors.
That doesn't seem right, since it works so much faster than that. Here's one citation that notes 100% CCR5 RO within hours...
Quote:
We observed no CCR5 RO on peripheral blood CD4+ T cells immediately prior to Leronlimab dosing, followed by 100% CCR5 RO within eight hours following the SC injection. CCR5 RO was then maintained at approximately 100% until the Leronlimab plasma concentration fell below 5 μg/mL at approximately six weeks post injection.
This is from a 2021 article by Sacha, Hansen, Recknor et al.
https://www.frontiersin.org/journals/immunolo...;id=794638
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