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Posted On: 07/18/2025 3:58:31 PM
Post# of 155764
From our FcRn abstract.
Experimental design to study transplacental mAb transfer rates:
* Importantly, rhesus macaques also express a conserved CCR5 receptor on CD4+ T cells, albeit at higher per-cell levels.
This enables the evaluation of CCR5 RO levels on blood CD4+ T cells as a measure of the mAb’s binding efficacy to the CCR5 receptor, leronlimab’s mechanism of action."
FcRn CD4+ T-cells cold/hot data...
Experimental design to study transplacental mAb transfer rates:
* Importantly, rhesus macaques also express a conserved CCR5 receptor on CD4+ T cells, albeit at higher per-cell levels.
This enables the evaluation of CCR5 RO levels on blood CD4+ T cells as a measure of the mAb’s binding efficacy to the CCR5 receptor, leronlimab’s mechanism of action."
FcRn CD4+ T-cells cold/hot data...
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