Math and the immune complement system? Useless or useful?

“The complement system is perhaps the oldest-known part of our extracellular immune system,” says Brenner. “It plays a crucial role in identifying foreign materials like microbes, medical devices, or new drugs—particularly the larger ones like in the COVID vaccine.”

The complement system can act as both protector and aggressor, offering defense on one side while harming the body on the other. In some cases, this ancient network worsens conditions like stroke by mistakenly targeting the body’s own tissues. As Brenner explains, when blood vessels leak, complement proteins can reach brain tissue, prompting the immune system to attack healthy cells and leading to worse outcomes for patients.

Now, through a combination of laboratory experiments, coupled differential equations, and computer-based modeling and simulations, an interdisciplinary team from the School of Engineering and Applied Science and the Perelman School of Medicine has uncovered the mathematical principles behind how the complement network “decides” to launch an attack.

https://scitechdaily.com/scientists-crack-the...ne-system/