sjacobs26, nice summary of CCR5 overexpression in TNBC and CRC. Just to add one other reference, you may want to review the CRC article I linked below.

https://pubmed.ncbi.nlm.nih.gov/30890699/

Here is an excerpt:

Quote:

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In human clinical specimens (n = 89), 20 cases (29%) were high for CCR5, whereas 69 cases (71%) were low. Statistical analyses indicated that CCR5 expression in primary CRC was associated with CRC patients' prognosis. Especially, stage III/IV patients with CCR5-high CRCs exhibited a significantly poorer prognosis than those with CCR5-low CRCs.

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