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Posted On: 05/15/2025 7:11:39 AM
Post# of 153174
Ya I got this, English would be nice.
“IFN-γ Upregulation: Increased T-cell/NK-cell activity in the TME likely boosts IFN-γ secretion. IFN-γ is a key driver of PD-L1 expression via the JAK/STAT pathway, as it activates transcription factors (e.g., IRF1) that bind the PD-L1 promoter.“
“IFN-γ Upregulation: Increased T-cell/NK-cell activity in the TME likely boosts IFN-γ secretion. IFN-γ is a key driver of PD-L1 expression via the JAK/STAT pathway, as it activates transcription factors (e.g., IRF1) that bind the PD-L1 promoter.“
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