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CytoDyn Inc CYDY
(Total Views: 419)
Posted On: 05/07/2025 7:13:41 AM
Post# of 154603
Posted By: ohm20
Re: kabonk #152413
Quote:
Not sure if they ever disclosed receptor occupancy versus dosage or LL concentration curve, have they?



Quote:
Finally, we extended these results to Leronlimab-treated humans and found that weekly 700 mg Leronlimab led to complete CCR5 RO on peripheral blood CD4+ T cells and a statistically significant increase in CCR5+CD4+ T cells in peripheral blood.
https://pubmed.ncbi.nlm.nih.gov/34868084/



Quote:
We observed complete CCR5 receptor occupancy in all donors by day 7.https://www.ijidonline.com/article/S1201-9712(20)32305-5/pdf



Until 2019 there wasn't a sensitive enough test to accurately determine CCR5 receptor occupancy. Patterson developed a flow cytometry one for Cytodyn.













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