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Does an initial normal low CCR5 site expression correlate with difficult to treat cancers such as tnbc?
And the converse?

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No, the hard to treat cancers are usually due to genetic mutations or locations that are difficult to treat.

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Are there sites with normal high CCR5 expression prior to cancer onset? Is LL best suited as a modulator of such cancer sites? TIA.
In cancers, is an increased or decreased CCR5 count the optimal treatment result?

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There's quite a wide range of normal CCR5 expression in various tissues. Basically the highest expression is in tissues that are more prone to exposure to pathogens. Lungs and stomach are very high and the lowest is the brain due to the blood/brain barrier. The normal expression size is of little import. A large rise from normal CCR5 expression means the tumor has hijacked the immune system and leronlimab can reverse that. A decreased CCR5 count is optimal.