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CytoDyn Inc CYDY
(Total Views: 8271)
Posted On: 03/19/2025 9:13:05 PM
Post# of 154948
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Posted By: Cycl2R
I don’t believe it has been noted here that the last letter strongly suggests that our new preclinical LL+ temozolomide follow-up to the disappointing lleronlimab-only GBM study has been yielding positive results.
Back in December Dr. Lalezari wrote:

Quote:
Lastly, the Company remains focused on the possible use of leronlimab in the treatment of GBM. Preliminary results from a preclinical study performed at the Albert Einstein College of Medicine do not appear to show a difference in outcome with leronlimab compared to the control arm. The Company has committed to repeating the study based on unpublished observations by Dr. Pestell’s lab and will now employ a treatment sequence involving temozolomide and leronlimab. This follow-up study will start immediately and should help clarify the potential therapeutic benefit of leronlimab in the treatment of GBM. CytoDyn is also currently in discussions with a key opinion leader in neuro-oncology about the possibility of initiating a pilot study in patients with GBM based on Dr. Pestell’s unpublished work and the outcome of the follow-up preclinical study

.

From the last letter:

Quote:
The Company also continues to explore the possible use of leronlimab in the treatment of glioblastoma multiforme (“GBM”). A preclinical study at the Albert Einstein College of Medicine sequencing temozolomide and leronlimab is now underway. CytoDyn is also in discussions with several KOLs in neuro-oncology about the possibility of initiating a pilot study in patients with GBM, also based on currently available data.



To me, “currently available” suggests that the study, presently about three months long, is still on!













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Whatever happens, we have got
Le-Ron-Li-Mab, and they have not.



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