Quote:

---

Ohm, I might be misrecollecting or disremembering, but have a shaky memory that only 70% of Leronlimab only crosses the brain blood barrier. If that's the case, could it be that the dosage would have to be rejiggered to fully occupy the CCR5 receptors within the brain?

---

A higher dosage would give opportunity for more leronlimab to pass. But you wouldn't want the shots to be over 350mg apiece due to a higher injection site reaction. However a more frequent dosage schedule than one week would accomplish the same thing.