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Posted On: 01/03/2025 2:50:45 AM
Post# of 155791
So my daughter is in Bali with Dengue Fever. I looked it up, and one paper I looked at was about:
They conclude that:
I think it's a longshot, because the following are not on Ohm's list:
But it just goes to show that excessive inflammation seems to be involved in virtually all kinds of disease, even hemorrhagic fevers.
Quote:
In this review, we discuss the dual role of the innate and inflammatory pathways activated during dengue disease in mediating both protection and exacerbation of disease. We show that some mediators involved in each of these responses differ substantially, suggesting that interfering in disease-associated immune pathways may represent a potential therapeutic opportunity for the treatment of severe dengue.
They conclude that:
Quote:
Of note, there is now evidence that severe dengue disease manifestation is associated with subversion of protective pathways by both viral and host factors, suggesting that altered host responses are directly involved in dengue disease severity. In addition, it appears that excessive inflammation, whether during primary or secondary cases of infection, contributes to the pathogenesis of severe dengue disease.
I think it's a longshot, because the following are not on Ohm's list:
Quote:
Some potential targets are Fc receptors, as well as some proinflammatory cytokine and chemokines, including CCR2 and CCR4 receptors. Moreover, PAFR blockade represents another novel target to modulate the inflammatory response
But it just goes to show that excessive inflammation seems to be involved in virtually all kinds of disease, even hemorrhagic fevers.
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