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Posted On: 12/09/2024 12:02:20 PM
Post# of 148863
Quote:
Hey, MGK. I would think it would come down to what's cheapest and easiest, a single AAV injection would do the trick. there ya go...no ART, no Bnabs needed.
I proposed that leronlimab could possibly achieve a cure over a 15 year time span if 100% or near 100% CCR5 coverage could be maintained. Because by then all reservoirs would be depleted. I thought that it may be achieved a bit quicker by use of other drugs that are known to accelerate reservoir depletion. It certainly wouldn't act quickly like the ART/Bnab/leronlimab combo. Either Bnabs or Bnabs working synergistically with leronlimab must have the ability to clear HIV viral reservoirs very fast.
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