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Posted On: 11/13/2024 4:19:47 PM
Post# of 151629
Quote:
HCM vaccination shifted the microglia phenotype from immune-suppression to inflammatory state. Further analysis of the effect of CCR5 knock out on the HCM vaccine survival efficacy are under current investigation.
Leronlimab shifts from immune-suppression (M2 macrophage/microglia) to inflammatory state (M1 macrophage/microglia) but limits the damaging effects of an inflammatory state by downregulating cytokines.


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