HCM vaccination shifted the microglia

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CytoDyn Inc CYDY

(Total Views: 464)

Posted On: 11/13/2024 4:19:47 PM

Post# of 148863

Posted By: ohm20

Re: mfglola #148008

Quote:
HCM vaccination shifted the microglia phenotype from immune-suppression to inflammatory state. Further analysis of the effect of CCR5 knock out on the HCM vaccine survival efficacy are under current investigation.

Leronlimab shifts from immune-suppression (M2 macrophage/microglia) to inflammatory state (M1 macrophage/microglia) but limits the damaging effects of an inflammatory state by downregulating cytokines.