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Posted On: 11/04/2024 11:30:40 PM
Post# of 148870
Saying it's not unmet need ?
There are many unmet medical needs for relapsed or refractory microsatellite stable (MSS) colorectal cancer (CRC), including:
Treatment options: There is a need for new treatment options that can provide lasting benefits for patients. Most patients with MSS mCRC do not respond to immunotherapy agents or do not have durable clinical responses.
Predictors of response: There is a need to obtain predictors of response to immunotherapy.
Combination therapies: There is a need to develop rational immunotherapy-based combination therapies.
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Cytodyn also mentions possibly using NSG.
Next-generation sequencing (NGS) is a genetic diagnostic technique that can help doctors understand a patient's cancer and select the best treatment. NGS can:
Identify mutations
NGS can analyze a tumor's DNA to pinpoint genetic mutations that are driving the cancer.
Predict treatment response
NGS can help doctors predict how a patient will respond to certain treatments.
Identify new markers
NGS can help identify new markers that may offer additional treatment options.
Save time and money
NGS can test many genes at once, which can save time and money compared to running multiple individual tests.
Detect mutations in blood
NGS can sometimes be performed on a patient's blood sample to detect small amounts of tumor DNA.
NGS is becoming a standard way to manage advanced cancer patients. It's based on high-throughput DNA sequencing technology that can analyze the entire genome, exome, or selected genes. NGS can be performed on tumor tissue or blood, and it can sequence DNA or RNA.
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Use to find Surrogate Marker ?
mssCRC sure's heck meets the advanced cancer
There are many unmet medical needs for relapsed or refractory microsatellite stable (MSS) colorectal cancer (CRC), including:
Treatment options: There is a need for new treatment options that can provide lasting benefits for patients. Most patients with MSS mCRC do not respond to immunotherapy agents or do not have durable clinical responses.
Predictors of response: There is a need to obtain predictors of response to immunotherapy.
Combination therapies: There is a need to develop rational immunotherapy-based combination therapies.
___
Cytodyn also mentions possibly using NSG.
Next-generation sequencing (NGS) is a genetic diagnostic technique that can help doctors understand a patient's cancer and select the best treatment. NGS can:
Identify mutations
NGS can analyze a tumor's DNA to pinpoint genetic mutations that are driving the cancer.
Predict treatment response
NGS can help doctors predict how a patient will respond to certain treatments.
Identify new markers
NGS can help identify new markers that may offer additional treatment options.
Save time and money
NGS can test many genes at once, which can save time and money compared to running multiple individual tests.
Detect mutations in blood
NGS can sometimes be performed on a patient's blood sample to detect small amounts of tumor DNA.
NGS is becoming a standard way to manage advanced cancer patients. It's based on high-throughput DNA sequencing technology that can analyze the entire genome, exome, or selected genes. NGS can be performed on tumor tissue or blood, and it can sequence DNA or RNA.
___
Use to find Surrogate Marker ?
mssCRC sure's heck meets the advanced cancer
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