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Posted On: 10/30/2024 6:12:00 PM
Post# of 148863
Quote:
With what drug would you think leronlimab would work better,
Resmetirom THR-Beta agonist or GLP-1 receptor agonist?
I don't think resmetirom will increase efficacy to any significant degree. A GLP-1 agonist might boost leromlimab's upregulation of GLP-1 to some extent further reducing liver fat. The combo might not be worthwhile if the increased reduction in fat from the agonist is small, due to the agonist's side effects.
Quote:
do you think a mixture of leronlimab with any of these glp-1 r agonists would be stable? or do you think the 2 medications would be injected with separate syringes in a final product.
I don't see them being combined in a shot if for no other reason than the volume of a leronlimab shot. At 700mg you already need two shots to keep site reaction minimal.
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