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Posted On: 10/20/2024 2:35:45 AM
Post# of 154806
Quote:
yes, that gene deletion means CCR5 is non functional. It doesn't work.
So if LL binds to it, it can do so, but that binding accomplishes nothing.
In CCR5 delta 32 double allele deletion CCR5 exists internally in the cell but is very rarely expressed on the surface of the cell so leronlimab cannot bind to it.
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