Chan was receiving radiation therapy until Aug 6th. Given the timeline of radiation/leronlimab treatments the greater part of that shrinkage is almost certainly due to radiation. The downside of radiation is the high rate of reoccurrence and the potential induction of metastasis.

Leronlimab however is a great idea to pair with radiation. CCR5 blockade would be helpful in many ways. It lowers factors that lead to metastasis. It represses the DNA repair that occurs after radiation and chemotherapy. It greatly curbs angiogenesis which is necessary for the tumor to regrow. It lowers tumor self protection mechanisms and increases natural killer T-cells to help kill the tumor.

With radiation treatment already done, from here on out we shall see what the effects of leronlimab are. A much slower than normal regrowth would show leronlimab having better effect than anything currently in use. A further shrinking of the tumor or even stasis would be excellent.