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Posted On: 07/26/2024 1:05:06 PM
Post# of 72445
The data Sheet
https://www.medchemexpress.com/Brilacidin.html
This link also includes:
MIC (MIC - Minimum Inhibitory Concentration - MIC90 - means 90% of isolates were inhibited in the 8 and 4 ug/mL range)
Brilacidin (PMX 30063) is an anti-infective antimicrobial with MIC90s of 1 and 8 μg/mL for Gram-positive bacteria Streptococcus pneumonia and Streptococcus viridans, and MIC90 of 8 and 4 μg/mL for Gram-negative bacteria Haemophilus influenza and Pseudomonas aeruginosa. Brilacidin is a defensin mimetic antibiotic compound.
Fact: It has stopped 11 strains of weaponized anthrax and countless other weaponized pathogens.
At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Brilacidin tetrahydrochloride) usually boasts enhanced water solubility and stability.
From the SDS ( Safety Data Sheet)
2. HAZARDS IDENTIFICATION
2.1 Classification of the substance or mixture
Not a hazardous substance or mixture.
2.2 GHS Label elements, including precautionary statements
Not a hazardous substance or mixture.
2.3 Other hazards
None.
https://www.medchemexpress.com/Brilacidin.html
This link also includes:
MIC (MIC - Minimum Inhibitory Concentration - MIC90 - means 90% of isolates were inhibited in the 8 and 4 ug/mL range)
Brilacidin (PMX 30063) is an anti-infective antimicrobial with MIC90s of 1 and 8 μg/mL for Gram-positive bacteria Streptococcus pneumonia and Streptococcus viridans, and MIC90 of 8 and 4 μg/mL for Gram-negative bacteria Haemophilus influenza and Pseudomonas aeruginosa. Brilacidin is a defensin mimetic antibiotic compound.
Fact: It has stopped 11 strains of weaponized anthrax and countless other weaponized pathogens.
At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Brilacidin tetrahydrochloride) usually boasts enhanced water solubility and stability.
From the SDS ( Safety Data Sheet)
2. HAZARDS IDENTIFICATION
2.1 Classification of the substance or mixture
Not a hazardous substance or mixture.
2.2 GHS Label elements, including precautionary statements
Not a hazardous substance or mixture.
2.3 Other hazards
None.
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