Investors Hangout Stock Message Boards Logo
  • Home
  • Mailbox
  • Boards
  • Favorites
  • Whats Hot!
  • Login - Join Now!
CytoDyn Inc CYDY
(Total Views: 19314)
Posted On: 07/24/2024 10:19:58 AM
Post# of 154916
Posted By: KenChowder
Re: MGK_2 #145275
I may not be reading the abstract right. Yes, two monkeys still had undetectable SHIV 70 weeks later. And yes, a third (of the four) monkeys started to make Leron on its own and has undetectable SHIV RNA a year later. But even the fourth monkey's story -- which sounds like the title of my next novel -- sounds pretty good, doesn't it? It also has detectable plasma Leron and declined plasma viremia.

So all four of the monkeys had good results, right? As in 100%?

Here's the part of the abstract about the two monkeys who developed anti-drug antibodies:

Quote:
The remaining two RMs developed ADAs within 5-15 weeks post-AAV resulting in complete clearance of Leronlimab from plasma as well as a rapid decline in CCR5 RO. Spontaneous reemergence of CCR5 RO by Leronlimab was observed approximately 1 year post-AAV. One of the two animals has had full and sustained CCR5 RO, detectable plasma Leronlimab, and undetectable SHIV RNA in plasma for over 1 year post-reexpression. The second re-expressing animal has achieved and maintained 100% CCR5 RO for about 10 weeks, has detectable plasma Leronlimab, and has declined plasma viremia.














(13)
(0)









  • New Post - Investors HangoutNew Post

  • Public Reply - Investors HangoutPublic Reply

  • Private Reply - Investors HangoutPrivate Reply

  • Board - Investors HangoutBoard

  • More - Investors HangoutMore

  • Keep Post - Investors HangoutKeep Post
  • Report Post - Investors HangoutReport Post
  • Home - Investors HangoutHome
  • Mailbox - Investors HangoutMailbox
  • Boards - Investors HangoutBoards
  • Favorites - Investors HangoutFavorites
  • Whats Hot! - Investors HangoutWhats Hot!
  • Settings - Investors HangoutSettings
  • Login - Investors HangoutLogin
  • Live Site - Investors HangoutLive Site