(Total Views: 677)
Posted On: 07/20/2024 1:15:35 AM
Post# of 154009
Award Notice Date 02-July-2024:
"To this end we will develop a novel formulation of long-acting Leronlimab that can be administered at home in a low volume able to provide coverage for three months."
"In specific aim 3, we will determine the length of time a single injection of the clinical dose can protect against vaginal transmission in cycling female macaques."
PROJECT NARRATIVE :
The development of a pre-exposure prophylactic reagent that potently inhibits transmitted HIV with minimal toxicity, lack of potential for drug-drug interactions, and infrequent dosing would greatly slow the HIV epidemic.
https://reporter.nih.gov/search/L2baW-idgEGE5...s/10876469
"To this end we will develop a novel formulation of long-acting Leronlimab that can be administered at home in a low volume able to provide coverage for three months."
"In specific aim 3, we will determine the length of time a single injection of the clinical dose can protect against vaginal transmission in cycling female macaques."
PROJECT NARRATIVE :
The development of a pre-exposure prophylactic reagent that potently inhibits transmitted HIV with minimal toxicity, lack of potential for drug-drug interactions, and infrequent dosing would greatly slow the HIV epidemic.
https://reporter.nih.gov/search/L2baW-idgEGE5...s/10876469
(10)
(0)
