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Previously Authorized Monoclonal Antibody Therapeutics critical to treating individuals and protecting some of our most vulnerable population... are NOT effective against currently circulating strains in the U.S.

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The monoclonal antibodies he is talking about targeted the original spike protein of Covid-19. Of course leronlimab never targeted the spike protein but handled the inflammatory effects that were killing people. The modified spike protein in variants does not change leronlimab's effectiveness.