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Resmetirom works to reduce intra-hepatic triglycerides. Reduction of steatosis. Main side effect is hepatotoxicity. Liver Function Tests need to be monitored during treatment.

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Meanwhile leronlimab lowered alanine aminotransferase, aspartate aminotransferase (AST) and alkaline phosphatase all enzymes that can can destroy the liver at very high levels. These are the same enzymes that can cause liver toxicity when using maraviroc.