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Posted On: 06/02/2024 8:00:18 PM
Post# of 148870
“At one time I thought of tracking down the complete pathways of everything connected to CCR5 but that could take a couple of years.”
OHM is right, it’s a rabbit hole and a PhD Thesis for Alice if she makes it out alive.
Based on everything I have read and coming from a medical background, for anyone interested in teasing out the connections you will find it invaluable to get a basic understanding of immunology first and then leverage the kind of articles that put a prism on the process. For example, I found this Nature article very useful and you will begin to understand how central NF-κB is to the inflammatory process. Take time to absorb figure 1, which shows the relationship to chemokines.
“NF-κB signaling in inflammation”
https://www.nature.com/articles/sigtrans201723
Failing this approach, matriculate with Alice on a PhD track in immunology.
OHM is right, it’s a rabbit hole and a PhD Thesis for Alice if she makes it out alive.
Based on everything I have read and coming from a medical background, for anyone interested in teasing out the connections you will find it invaluable to get a basic understanding of immunology first and then leverage the kind of articles that put a prism on the process. For example, I found this Nature article very useful and you will begin to understand how central NF-κB is to the inflammatory process. Take time to absorb figure 1, which shows the relationship to chemokines.
“NF-κB signaling in inflammation”
https://www.nature.com/articles/sigtrans201723
Failing this approach, matriculate with Alice on a PhD track in immunology.
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