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Posted On: 05/17/2024 12:33:42 AM
Post# of 148870
Quote:
Are they resurrecting this trial (NCT05730673)?
Possibly, although the drug pairing of regorafenib may add little to the effect of leronlimab. Regorafenib inhibits the protein TIE2 which then downregulates VEGF which slows angiogenesis and tumor growth. Leronlimab also downregulates VEGF with the same results.
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