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There was an article in Nature on 5/1/24 entitled “Found: the dial in the brain that controls the immune system”.

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On the inflammatory side their are a couple of neuropeptides that increase the motility of intracellular calcium, driving an increase in inflammatory cytokines. On the anti-inflammatory side elevated IL-1b and TNF trigger the vagus nerve which produces anti-inflammatory cytokines to try to balance things out. As we know things often go awry. Too much intracellular calcium and not a large enough response from the vagus nerve you have a cytokine storm. An overreaction from the vagus nerve and you'll have immune suppression.

I think it will be quite awhile before you see any treatments developed that try to control immune response neuronally. It will be very tricky to balance things out so you don't have an overreaction or underreaction. Leronlimab is a little less direct method of controlling the immune system but that gives it the benefit of allowing a normal immune response.