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Posted On: 03/06/2024 10:14:31 AM
Post# of 148870
Plotinus,
I agree with your post re: infusion dosage. Just a note to add.
Likely, we achieved 100% RO somewhere between 525 and 700mg. The extra LL floating around probable caused a little diarrhea. We may never know the exact mg to dose, it may not matter as each patient will be expressing CCR5 in different amounts.
“You would not be bound by the current practical limit of 700 mg SQ…I think that is a 2mL volume, a pretty large volume to be pushing in SQ…IV infusion could entertain much higher dosing as determined through further study based on indication,…”
Surely would have peaked quickly in severe Covid folks.
Investors Hangout: https://investorshangout.com/post/view?id=667...z8ThxiSKIr
I agree with your post re: infusion dosage. Just a note to add.
Likely, we achieved 100% RO somewhere between 525 and 700mg. The extra LL floating around probable caused a little diarrhea. We may never know the exact mg to dose, it may not matter as each patient will be expressing CCR5 in different amounts.
“You would not be bound by the current practical limit of 700 mg SQ…I think that is a 2mL volume, a pretty large volume to be pushing in SQ…IV infusion could entertain much higher dosing as determined through further study based on indication,…”
Surely would have peaked quickly in severe Covid folks.
Investors Hangout: https://investorshangout.com/post/view?id=667...z8ThxiSKIr
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