(Total Views: 601)
Posted On: 02/08/2024 5:43:02 AM
Post# of 154913
So direct primary blocking of CCR5 downregulates indirectly or secondarily:
RANTES or CCL5 (reduced NK cell deception)
Intracellular CA2+ (reduced manufacture of NFAT)
NFAT (reduced intracellular CA2+)
IFNy (reduced inflammation)
PD-L1 (reduced tumor sparing)
and other inflammatory chemokines (reduced inflammation)
RANTES or CCL5 (reduced NK cell deception)
Intracellular CA2+ (reduced manufacture of NFAT)
NFAT (reduced intracellular CA2+)
IFNy (reduced inflammation)
PD-L1 (reduced tumor sparing)
and other inflammatory chemokines (reduced inflammation)
(2)
(0)
