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Posted On: 02/06/2024 2:47:19 PM
Post# of 154145
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My question really is How does CCR5 block PD-L1? Is it a direct interaction or an indirect one?
CCr5 blockade would downregulate PD-L1 via downregulation of IFNy.
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Also, ohm, could you please re-direct me back to that paper you got that image from?
CCR5 blockade inflames antitumor immunity in BAP1-mutant clear cell renal cell carcinoma
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228663/
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