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Posted On: 11/18/2023 12:18:15 AM
Post# of 148870
Quote:
going to also fantasize that leronlimab is MORE effective than keytruda
We've seen the data for PD-1 (the chemokine that attaches to PD-L1 (Keytruda's target)) downregulation by maraviroc. Leronlimab also inhibits angiogenisis, anti-trafficking of tumor cells, increase in tumor fighting NKT cells, crippling DNA repair in tumor cells, stopping recruitment of Tregs (which keeps the immune system from killing tumor cells), downregulates IL-4 and IL-13 (tumor protectants), downregulates CDK2/4/6, cyclin D1, cyclin E, and PCNA which are implicated in tumor cell growth, Upregulates p27 and p53 which are both tumor suppressors.
No need to fantasize. I have no doubt that leronlimab far outclasses Keytruda and can fight cancers that Keytruda has failed in.
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