Regulated by leronlimab -

IL-1b (via caspase-1 downreg)[-]

Quote:

---

When researchers artificially reduced the number of T regulatory (Treg) cells – known to help keep the immune system in check – some of the same effects were observed, opening a possible route that future treatments could take.

"Both menthol exposure and Treg cell blockade caused a decrease in IL-1β, a protein that could be behind the cognitive decline observed in these models," said neuroscientist Ana Garcia-Osta, from CIMA, at the time.
https://www.sciencealert.com/mouse-study-reve...alzheimers

---

Leronlimab also causes a significant reduction in Tregs. p value = .0123

Quote:

---

Percent of total immune cells in long-term Leronlimab treatment in humans

---