Here is another mechanism, showing how Leronlimab can help cognitive impairment. Klotho, a kidney protein found in the blood, helps primate cognitave ability in aging primates. CCL5 is shown to down regulate Klotho production. Know what you own!

https://www.nature.com/articles/s43587-023-00441-x

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922032/