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Posted On: 06/23/2023 11:14:12 AM
Post# of 148878
Excerpt: In this study, we identified CCL3, CCL4, and CCL5 and their
cognate receptor CCR5 as mediators of a new detrimental
crosstalk between microglia and neurons, which suppresses
neuronal autophagy via mTORC1 activation and impairs the
clearance of aggregate-prone proteins.
https://www.cell.com/neuron/pdf/S0896-6273(23)00268-4.pdf
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