Adding a little more color on CAR-T and cytokine release syndrome to emphasize what a gift Leronlimab would be: patient’s often don’t qualify for this expensive therapy unless they have failed often several other chemo regimens. At that point they become medically complex, think renal failure, challenges with hemoglobin, platelets and electrolytes. CAR-T can be curative for things like multiple myeloma, a huge gift for these patients, but…if CRS makes an appearance it can take an unstable patient and put them through the inner circle of hell: high fevers, 106-107 degrees, delirium, seizures…don’t recognize their spouse. Aphasia, elevated ferritin and CRP. They need a drug to get them through this challenging passage to get to the other side and revel in a potential cure. That drug is Leronlimab.