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Posted On: 12/27/2022 7:50:21 PM
Post# of 148870
From the study on cause of Alzheimer's:
“The immune cells appear to be a little angry in older individuals,” Gate said. “We think this anger might make these cells less functional, resulting in dysregulation of the brain’s immune system.”
In the cognitively impaired group, inflamed T-cells cloned themselves and flowed into the CSF and brain as if they were following a radio signal, Gate said. Scientists found the cells had an overabundance of a cell receptor — CXCR6 — that acts as an antenna. This receptor receives a signal — CXCL16 — from the degenerating brain’s microglia cells to enter the brain.
“The immune cells appear to be a little angry in older individuals,” Gate said. “We think this anger might make these cells less functional, resulting in dysregulation of the brain’s immune system.”
In the cognitively impaired group, inflamed T-cells cloned themselves and flowed into the CSF and brain as if they were following a radio signal, Gate said. Scientists found the cells had an overabundance of a cell receptor — CXCR6 — that acts as an antenna. This receptor receives a signal — CXCL16 — from the degenerating brain’s microglia cells to enter the brain.
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