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But a higher dose at 700mg may have had an additional negative affect on other cytokines. A few Interleukins as I recall.

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Strange that the heat map shows increases in IL-6 and TNF-a at 700 mg. In Covid both Yang and Patterson saw decreases in IL-6 and Patterson saw decreases in TNF-a (unknown whether Yang tested for it).

That would certainly suggest that there are other confounding factors and it isn't due to an increased dosage having a lesser effect.