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Posted On: 06/25/2022 1:08:32 PM
Post# of 154130
More in Nature on CCR5 and memory formation, citing maraviroc in mice:
"Our findings also show that an age-related increase in the neuronal expression of CCR5 and its ligand CCL5 leads to impairments in memory linking in aged mice, which could be reversed with a Ccr5 knockout and a drug approved by the US Food and Drug Administration (FDA) that inhibits this receptor, a result with clinical implications."
https://www.nature.com/articles/s41586-022-04783-1
"Our findings also show that an age-related increase in the neuronal expression of CCR5 and its ligand CCL5 leads to impairments in memory linking in aged mice, which could be reversed with a Ccr5 knockout and a drug approved by the US Food and Drug Administration (FDA) that inhibits this receptor, a result with clinical implications."
https://www.nature.com/articles/s41586-022-04783-1
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