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Posted On: 06/14/2022 10:41:44 AM
Post# of 148899
Another way that CCR5 induces NASH. CCL5 binding to CCR5 promotes the migration of adenosine deaminase 2 (ADA2) to the liver. ADA2 then upregulates platelet derived growth factor-B (PDGF-
which is a primary pro-fibrotic cytokine. Leronlimab of course stops the migration of ADA2 bearing monocytes.
It took me a bit of time to trace that one out.
which is a primary pro-fibrotic cytokine. Leronlimab of course stops the migration of ADA2 bearing monocytes. It took me a bit of time to trace that one out.
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