Viridi writes: "Uhhh, no. Please feel free to cite your source."

Uhhhhh, that's an impolite response, which may or may not deserve an answer, but my source was a paper in the NIH's National Library of Medicine -- the National Center for Biotechnology Information: https://pubmed.ncbi.nlm.nih.gov/24680255/#:~:...spectively.

"About 50% and less than 10% of patients infected with HIV-1 have multidrug and multiclass resistance linked to 16 antiretroviral drugs, respectively."

Not a new paper, but in all likelihood drug resistance would rise over time.