CCR5 has been studied for long time in connection with brain enhancement (cognitive & memory) and inflammation playing a major role in the brain.

Below an article “China’s CRISPR twins might have had their brains inadvertently enhanced “: about the twins Lulu and Nana (not the original names) who were “CRISPRed” by He Jiankui before birth to make them immune to HIV infection.

Below some quotes from the article:

https://www.technologyreview.com/2019/02/21/1...s-altered/

Quote:

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Although He never consulted the brain researchers, the Chinese scientist was certainly aware of the link between CCR5 and cognition. It was first shown in 2016 by Zhou and Silva, who found that removing the gene from mice significantly improved their memory. The team had looked at more than 140 different genetic alterations to find which made mice smarter.

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Quote:

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According to their new report, appearing in the journal Cell, people who naturally lack CCR5 recover more quickly from strokes . What’s more, people missing at least one copy of the gene seem to go further in school , suggesting a possible role in everyday intelligence.

“We are the first to report a function of CCR5 in the human brain, and the first to report a higher level of education,” says UCLA biologist S. Thomas Carmichael, who led the new study. He calls the link to educational success “ tantalizing ” but says it needs further study.

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Quote:

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The discoveries about CCR5 are already being followed up in drug trials on both stroke patients and people with HIV, who sometimes suffer memory problems. In those studies, one of which is under way at UCLA, people are being given an anti-HIV drug, Maraviroc, which chemically blocks CCR5, to see if it improves their cognition.

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Also, there seems to be a link to CCR5 for those who possess the so, called, photographic memory, link that was elaborated in a PhD Thesis.

In summary, as you can see, brains and CCR5 are highly interwingled (pun and joke intended).

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