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Posted On: 05/26/2022 3:03:42 AM
Post# of 148908
Quote:
I don't believe Maraviroc crosses the blood brain barrier. If Ohm would confirm this, it would be appreciated.
Maraviroc is small molecule so it can pass easier in an inflammatory state. The downside to maraviroc is it's lower receptor occupancy which means a much lower efficacy than leronlimab. Then of course there's the SAE liver problems.
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