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Posted On: 02/22/2022 6:07:18 PM
Post# of 148938
I first posted about the potential of leronlimab to cure HIV by forcing HIV out of reservoirs and blocking CCR5 a few years ago. It's become much more likely now with an effective drug to force the reservoirs. The doctors used injected natural killer T cells but blocking all CCR5 receptors or that in combination with NKT cells should be more effective.
Quote:
UCLA-led team refines ‘kick and kill’ strategy aimed at eliminating HIV-infected cells
The UCLA-led study continues research on a strategy called “kick and kill,” which many of the same scientists first described in a 2017 paper. The approach coaxes the dormant virus to reveal itself in infected cells, so it can then be targeted and killed.
In the new study, while the mice were receiving antiretrovirals, the researchers used SUW133 to flush HIV infected cells out of hiding. They then injected healthy natural killer cells into the mice’s blood to kill the infected cells. The combination of SUW133 and injections of healthy natural killer immune cells completely cleared the HIV in 40% of the HIV-infected mice.
https://www.uclahealth.org/ucla-led-team-refi...tegy-aimed
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